Fourteen Afghan security forces were killed and nine wounded when the vehicle exploded.
It was reported that the victims of the attack include women, students and police were confirmed by the Hedayatullah Hamidi, public health director in Gardez.
Tolo News quoted Afghanistan's Ministry of Interior (MoI) as saying that insurgents targeted the police training academy close to the police headquarters.
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National rates also followed a similar pattern, with the number of teens involved in deadly crashes dropping almost 43 percent. The week is meant to highlight motor vehicle crashes as being the leading cause of death in teenagers in North Carolina.
The attack was one of at least two Taliban attacks on police stations on Tuesday. The attack came hours after a USA drone strike in Pakistan's Kurram tribal district, part of which borders Paktia, killed at least 26 Haqqani militants, officials have said.
A reporter at the scene with the local TOLOnews agency said heavy fighting was ongoing on Tuesday.
Photos posted on Twitter purportedly show two large plumes of smoke rising above the city, suggesting two bombs were detonated in the assault.
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U.S. President Donald Trump recently unveiled a strategy to try to defeat the militants, and officials said more than 3,000 additional U.S. troops are being sent to Afghanistan to reinforce the 11,000 already stationed there.
In June 2017, the Taliban carried out an attack with same style at police headquarter in the same city Gardez killing dozens of people and leaving scores injured.
The latest attacks comes as four-way talks between Afghanistan, Pakistan, the United States and China reportedly are being held in Oman with the aim of ending the Taliban's 16-year insurgency.
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If a tumor is hormone receptor-positive, that means its growth is fueled by certain hormones, according to the ACS. In other words, these factors together accounted for 75% of the total excess risk of death in black patients.