Too much Ibuprofen linked to male infertility


Within 14 days, testosterone-producing hormones in the men taking ibuprofen dropped, causing compensated hypogonadism, according to USA Today .

Ibuprofen is a nonsteroidal anti-inflammatory drug and is taken by athletes both to prevent and treat pain. They will try to find out whether the men taking lower doses of ibuprofen are also facing same hormonal effects or not, said study co-author Bernard Jégou, director of the National Institute for Research on Environmental and Occupational Health in France.

"Ibuprofen appears to be the preferred pharmaceutical analgesic for long-term chronic pain and arthritis", the research team is quoted as saying by the Daily Mail.

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Though the exact reasons for the decline are not yet known; in a recent study, researchers have linked male infertility to Ibuprofen - a common painkiller. These could include the development of congenital malformations, which is what led the researchers to wonder how the drugs would affect adults.

As it relieves pain, ibuprofen may also diminish male fertility, according to a small but compelling new study.

"Our immediate concern is for the fertility of men who use these drugs for a long time", researcher David Møbjerg Kristensen from the University of Copenhagen in Denmark told The Guardian. Inhibition of testosterone levels was found to be significant and dose-dependent after 24 and 48 hours of ibuprofen exposure (in doses which corresponded to the oral doses used in the trial). Ask the average person whether ibuprofen is risky and they'll likely say it is safe when used properly, but that may not be true. The experimental group received ibuprofen twice a day for a total of six weeks and was tested for hormone levels at two and six weeks.

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Scientists warn that ibuprofen could be wrecking men's fertility by making their balls shrivel up.

The study was published on Monday in the journal Proceedings of the National Academy of Sciences. (The rest of the volunteers were given a placebo.) Within two weeks, the group of 14 had developed compensated hypogonadism, which along with lowered fertility is also associated with depression, heart failure and stroke.

In a shocking study, ibuprofen has been proven to have severe negative impact on male fertility especially on their testicles. However, long term effects of long term use of Ibuprofen may not be reversible he added. Until now, it has been primarily linked to adverse effects such as gastrointestinal bleeding, cardiovascular disorders and kidney damage.

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