"We want them to get the highest care and the care that they so richly deserve", Trump said before he signed the order in the Oval Office.
The White House said Trump will not undergo a psychiatric exam. Officials did not address a different type of screening: assessments of cognitive status that examine neurologic functions including memory.
In that September 2016 program, a letter from Trump's longtime personal physician, Harold Bornstein, revealed that Trump was 6 feet, 3 inches tall and weighed 236 pounds, ABC News reported.
Trump himself hit out at claims over his mental capacity, tweeting on Saturday that he was a 'very stable genius'.
Trump's checkup comes amid questions about his health and publication of the new book, "Fire and Fury: Inside the Trump White House", which casts doubt on Trump's fitness for office.
The book has been dismissed as "tabloid trash" by the White House.
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Trump, 71, is the oldest first-term president.
The medical checkup at Walter Reed Medical Center in nearby Bethesda, Maryland, will be the first for Trump since he took office almost a year ago.
Trump takes a statin to control cholesterol, baby aspirin to prevent heart attacks and Propecia to treat male-pattern baldness. When asked about it, White House press secretary Sarah Huckabee Sanders said questions about Trump's health were "frankly, pretty ridiculous" and blamed his slurred speech on a dry throat, "nothing more than that".
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Still, the decision to schedule a physical for this coming Friday was ultimately up to Trump.
Obama underwent four periodic physical exams as president. The doctor's 2016 letter stated that Trump's testosterone level, 441.6, was in the normal range, as were his PSA reading for prostate abnormalities and tests of his liver and thyroid.
Why is Donald Trump undergoing a physical? He also played golf and indulged in Big Macs. Dr. Ronny Jackson, the White House physician who will oversee the procedure, is scheduled to discuss the results at a press briefing next Tuesday. Physicians have provided care to presidents since George Washington was in office, and Congress created the formal title of White House physician in 1928.
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Goggins, who presented the award , had to awkwardly step back to the microphone and accept the award on Franco's behalf. Yvonne Strahovski of " The Handmaid's Tale " was among those who selected a colorful, patterned dress for the affair.
Jackson, Trump's physician, is a Navy rear admiral who was the emergency medicine doctor for a shock trauma platoon in Taqaddum, Iraq, during Operation Iraqi Freedom, according to his Navy bio.